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The Regulatory Status Adopted by Lymph Node Dendritic Cells and T Cells During Healthy Aging Is Maintained During Cancer and May Contribute to Reduced Responses to Immunotherapy

Aging is associated with an increased incidence of cancer. One contributing factor could be modulation of immune cells responsible for anti-tumor responses, such as dendritic cells (DCs) and T cells. These immunological changes may also impact the efficacy of cancer immunotherapies in the elderly. T...

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Detalhes bibliográficos
Publicado no:Front Med (Lausanne)
Main Authors: Gardner, Joanne K., Jackaman, Connie, Mamotte, Cyril D. S., Nelson, Delia J.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6287204/
https://ncbi.nlm.nih.gov/pubmed/30560130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmed.2018.00337
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