VEGFB/VEGFR1-Induced Expansion of Adipose Vasculature Counteracts Obesity and Related Metabolic Complications

Impaired angiogenesis has been implicated in adipose tissue dysfunction and the development of obesity and associated metabolic disorders. Here, we report the unexpected finding that vascular endothelial growth factor B (VEGFB) gene transduction into mice inhibits obesity-associated inflammation and...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Cell Metab
Prif Awduron: Robciuc, Marius R., Kivelä, Riikka, Williams, Ian M., de Boer, Jan Freark, van Dijk, Theo H., Elamaa, Harri, Tigistu-Sahle, Feven, Molotkov, Dmitry, Leppänen, Veli-Matti, Käkelä, Reijo, Eklund, Lauri, Wasserman, David H., Groen, Albert K., Alitalo, Kari
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2016
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5898626/
https://ncbi.nlm.nih.gov/pubmed/27076080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2016.03.004
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