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Diverse Redoxome Reactivity Profiles of Carbon Nucleophiles
Targeted covalent inhibitors have emerged as a powerful approach in the drug discovery pipeline. Key to this process is the identification of signaling pathways (or receptors) specific to (or overexpressed in) disease cells. In this context, fragment-based ligand discovery (FBLD) has significantly e...
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| Publicat a: | J Am Chem Soc |
|---|---|
| Autors principals: | , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2017
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5898444/ https://ncbi.nlm.nih.gov/pubmed/28355876 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.7b01791 |
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