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Diverse Redoxome Reactivity Profiles of Carbon Nucleophiles

Targeted covalent inhibitors have emerged as a powerful approach in the drug discovery pipeline. Key to this process is the identification of signaling pathways (or receptors) specific to (or overexpressed in) disease cells. In this context, fragment-based ligand discovery (FBLD) has significantly e...

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Bibliografske podrobnosti
izdano v:J Am Chem Soc
Main Authors: Gupta, Vinayak, Yang, Jing, Liebler, Daniel C., Carroll, Kate S.
Format: Artigo
Jezik:Inglês
Izdano: 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5898444/
https://ncbi.nlm.nih.gov/pubmed/28355876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.7b01791
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