Proteolytic biomarkers are related to prognosis in COPD- report from a population-based cohort

BACKGROUND: The imbalance between proteases and anti-proteases is considered to contribute to the development of COPD. Our aim was to evaluate the protease MMP-9, the antiprotease TIMP-1 and the MMP-9/TIMP-1-ratio as biomarkers in relation to prognosis. Prognosis was assessed as lung function declin...

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Vydáno v:Respir Res
Hlavní autoři: Linder, Robert, Rönmark, Eva, Pourazar, Jamshid, Behndig, Annelie F., Blomberg, Anders, Lindberg, Anne
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2018
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5897990/
https://ncbi.nlm.nih.gov/pubmed/29650051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12931-018-0772-5
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