Brain Iron Distribution after Multiple Doses of Ultra-small Superparamagnetic Iron Oxide Particles in Rats

The purpose of this study is to determine the effects of high cumulative doses of ultra-small paramagnetic iron oxide (USPIO) used in neuroimaging studies. We intravenously administered 8 mg/kg of 2 USPIO compounds daily for 4 wk to male Sprague–Dawley rats (Crl:SD). Multiecho gradient-echo MRI, ser...

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Detaylı Bibliyografya
Yayımlandı:Comp Med
Asıl Yazarlar: Gorman, Andrew W, Deh, Kofi M, Schwiedrzik, Caspar M, White, Julie R, Groman, Ernest Victor, Fisher, Clark A, Gillen, Kelly M, Spincemaille, Pascal, Rasmussen, Skye, Prince, Martin R, Voss, Henning U, Freiwald, Winrich A, Wang, Yi
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Association for Laboratory Animal Science 2018
Konular:
Rat Model
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5897970/
https://ncbi.nlm.nih.gov/pubmed/29663939
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