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Proteome-wide mapping of PQS-interacting proteins in Pseudomonas aeruginosa

The opportunistic human pathogen Pseudomonas aeruginosa secretes 2-heptyl-3-hydroxy-4-quinolone (PQS), a quorum sensing (QS) signal that regulates the expression of numerous virulence genes. Here we report the development and application of chemical probes to globally map quinolone binding proteins....

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Publicat a:Chem Sci
Autors principals: Dandela, Rambabu, Mantin, Danielle, Cravatt, Benjamin F., Rayo, Josep, Meijler, Michael M.
Format: Artigo
Idioma:Inglês
Publicat: Royal Society of Chemistry 2018
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5897874/
https://ncbi.nlm.nih.gov/pubmed/29719702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c7sc04287f
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