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Can genetics resolve what Notch does in HSCs?
The effects of Notch signaling in hematopoietic stem and progenitor cells remain controversial. In work presented in this issue of Blood, Duarte et al interfere genetically with the Notch transcriptional complex (NTC) in hematopoiesis and demonstrate that canonical Notch signals are dispensable in p...
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| Publié dans: | Blood |
|---|---|
| Auteurs principaux: | , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society of Hematology
2018
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5897870/ https://ncbi.nlm.nih.gov/pubmed/29650730 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2018-02-829069 |
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