Early Retinal Defects in Fmr1(−/y) Mice: Toward a Critical Role of Visual Dys-Sensitivity in the Fragile X Syndrome Phenotype?

Fragile X Syndrome (FXS) is caused by a deficiency in Fragile X Mental Retardation Protein (FMRP) leading to global sensorial abnormalities, among which visual defects represent a critical part. These visual defects are associated with cerebral neuron immaturity especially in the primary visual cort...

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Veröffentlicht in:Front Cell Neurosci
Hauptverfasser: Perche, Olivier, Felgerolle, Chloé, Ardourel, Maryvonne, Bazinet, Audrey, Pâris, Arnaud, Rossignol, Rafaëlle, Meyer-Dilhet, Géraldine, Mausset-Bonnefont, Anne-Laure, Hébert, Betty, Laurenceau, David, Montécot-Dubourg, Céline, Menuet, Arnaud, Bizot, Jean-Charles, Pichon, Jacques, Ranchon-Cole, Isabelle, Briault, Sylvain
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2018
Schlagworte:
Neuroscience
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5897671/
https://ncbi.nlm.nih.gov/pubmed/29681800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2018.00096
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