Sirtuin 7 Deficiency Ameliorates Cisplatin-induced Acute Kidney Injury Through Regulation of the Inflammatory Response

Cisplatin-induced acute kidney injury (AKI) has been recognized as one of cisplatin’s serious side effects, limiting its use in cancer therapy. Sirtuin 1 (SIRT1) and SIRT3 play protective roles against cisplatin-induced kidney injury. However, the role of SIRT7 in cisplatin-induced kidney injury is...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Miyasato, Yoshikazu, Yoshizawa, Tatsuya, Sato, Yoshifumi, Nakagawa, Terumasa, Miyasato, Yuko, Kakizoe, Yutaka, Kuwabara, Takashige, Adachi, Masataka, Ianni, Alessandro, Braun, Thomas, Komohara, Yoshihiro, Mukoyama, Masashi, Yamagata, Kazuya
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2018
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5897539/
https://ncbi.nlm.nih.gov/pubmed/29651144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-24257-7
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