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VDAC1 as Pharmacological Target in Cancer and Neurodegeneration: Focus on Its Role in Apoptosis

Cancer and neurodegeneration are different classes of diseases that share the involvement of mitochondria in their pathogenesis. Whereas the high glycolytic rate (the so-called Warburg metabolism) and the suppression of apoptosis are key elements for the establishment and maintenance of cancer cells...

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Publicat a:Front Chem
Autors principals: Magrì, Andrea, Reina, Simona, De Pinto, Vito
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2018
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5897536/
https://ncbi.nlm.nih.gov/pubmed/29682501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fchem.2018.00108
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