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Novel Compounds Targeting the Mitochondrial Protein VDAC1 Inhibit Apoptosis and Protect against Mitochondrial Dysfunction

Apoptosis is thought to play a critical role in several pathological processes, such as neurodegenerative diseases (i.e. Parkinson's and Alzheimer's diseases) and various cardiovascular diseases. Despite the fact that apoptotic mechanisms are well defined, there is still no substantial the...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:J Biol Chem
Main Authors: Ben-Hail, Danya, Begas-Shvartz, Racheli, Shalev, Moran, Shteinfer-Kuzmine, Anna, Gruzman, Arie, Reina, Simona, De Pinto, Vito, Shoshan-Barmatz, Varda
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Biochemistry and Molecular Biology 2016
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC5122769/
https://ncbi.nlm.nih.gov/pubmed/27738100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.744284
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