Increased O-GlcNAcylation of Endothelial Nitric Oxide Synthase Compromises the Anti-contractile Properties of Perivascular Adipose Tissue in Metabolic Syndrome

Under physiological conditions, the perivascular adipose tissue (PVAT) negatively modulates vascular contractility. This property is lost in experimental and human obesity and in the metabolic syndrome, indicating that changes in PVAT function may contribute to vascular dysfunction associated with i...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Front Physiol
Prif Awduron: da Costa, Rafael M., da Silva, Josiane F., Alves, Juliano V., Dias, Thiago B., Rassi, Diane M., Garcia, Luis V., Lobato, Núbia de Souza, Tostes, Rita C.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Frontiers Media S.A. 2018
Pynciau:
Physiology
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5897513/
https://ncbi.nlm.nih.gov/pubmed/29681862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2018.00341
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