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ParaCEST Agents Encapsulated in Reverse Nano-Assembled Capsules (RACs): How Slow Molecular Tumbling Can Quench CEST Contrast

Although paraCEST is a method with immense scope for generating image contrast in MRI, it suffers from the serious drawback of high detection limits. For a typical discrete paraCEST agent the detection limit is roughly an order of magnitude higher than that of a clinically used relaxation agent. One...

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Detalhes bibliográficos
Publicado no:Front Chem
Main Authors: Farashishiko, Annah, Slack, Jacqueline R., Botta, Mauro, Woods, Mark
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5897432/
https://ncbi.nlm.nih.gov/pubmed/29682499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fchem.2018.00096
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