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Design principles for enhancing phase sensitivity and suppressing phase fluctuations simultaneously in biochemical oscillatory systems

Biological systems need to function accurately in the presence of strong noise and at the same time respond sensitively to subtle external cues. Here we study design principles in biochemical oscillatory circuits to achieve these two seemingly incompatible goals. We show that energy dissipation can...

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Bibliografiske detaljer
Udgivet i:Nat Commun
Main Authors: Fei, Chenyi, Cao, Yuansheng, Ouyang, Qi, Tu, Yuhai
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5897384/
https://ncbi.nlm.nih.gov/pubmed/29651016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-03826-4
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