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Design principles for enhancing phase sensitivity and suppressing phase fluctuations simultaneously in biochemical oscillatory systems

Biological systems need to function accurately in the presence of strong noise and at the same time respond sensitively to subtle external cues. Here we study design principles in biochemical oscillatory circuits to achieve these two seemingly incompatible goals. We show that energy dissipation can...

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Pubblicato in:Nat Commun
Autori principali: Fei, Chenyi, Cao, Yuansheng, Ouyang, Qi, Tu, Yuhai
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5897384/
https://ncbi.nlm.nih.gov/pubmed/29651016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-03826-4
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