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Epigenetic activation during T helper 17 cell differentiation is mediated by Tripartite motif containing 28
Epigenetic regulation is important for T-cell fate decision. Although STAT3 is known to initiate Th17 differentiation program, the downstream mechanism is unclear. Here we show that Tripartite motif containing 28 (Trim28) expression in Th17 cells is required for Th17-mediated cytokine production and...
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| Publicado no: | Nat Commun |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5897371/ https://ncbi.nlm.nih.gov/pubmed/29651155 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-03852-2 |
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