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Mitochondrial function and autophagy: integrating proteotoxic, redox, and metabolic stress in Parkinson’s disease

Parkinson’s disease (PD) is a movement disorder with widespread neurodegeneration in the brain. Significant oxidative, reductive, metabolic, and proteotoxic alterations have been observed in PD postmortem brains. The alterations of mitochondrial function resulting in decreased bioenergetic health is...

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Detalhes bibliográficos
Publicado no:J Neurochem
Main Authors: Zhang, Jianhua, Culp, M Lillian, Craver, Jason G, Darley-Usmar, Victor
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5897151/
https://ncbi.nlm.nih.gov/pubmed/29341130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jnc.14308
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