Mapping surface residues of eIF5A that are important for binding to the ribosome using alanine scanning mutagenesis

The translation elongation factor eIF5A is conserved through evolution and is necessary to rescue the ribosome during translation elongation of polyproline-containing proteins. Although the site of eIF5A binding to the ribosome is known, no systematic analysis has been performed so far to determine...

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Bibliografiske detaljer
Udgivet i:Amino Acids
Main Authors: Barbosa, Natália M., Boldrin, Paulo E. G., Rossi, Danuza, Yamamoto, Priscila A., Watanabe, Tatiana F., Serrão, Vitor H., Hershey, John W. B., Fraser, Christopher S., Valentini, Sandro R., Zanelli, Cleslei F.
Format: Artigo
Sprog:Inglês
Udgivet: 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5897047/
https://ncbi.nlm.nih.gov/pubmed/27388480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00726-016-2279-z
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