Evidence for a Negative Cooperativity between eIF5A and eEF2 on Binding to the Ribosome

eIF5A is the only protein known to contain the essential and unique amino acid residue hypusine. eIF5A functions in both translation initiation due to its stimulation of methionyl-puromycin synthesis and translation elongation, being highly required for peptide-bound formation of specific ribosome s...

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Publicat a:PLoS One
Autors principals: Rossi, Danuza, Barbosa, Natalia M., Galvão, Fabio C., Boldrin, Paulo E. G., Hershey, John W. B., Zanelli, Cleslei F., Fraser, Christopher S., Valentini, Sandro R.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2016
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4845985/
https://ncbi.nlm.nih.gov/pubmed/27115996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0154205
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