Actomyosin-mediated tension orchestrates uncoupled respiration in adipose tissues

The activation of brown/beige adipose tissue (BAT) metabolism and the induction of uncoupling protein-1 (UCP1) expression are essential for BAT-based strategies to improve metabolic homeostasis. Here, we demonstrate that BAT utilizes actomyosin machinery to generate tensional responses following adr...

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Detalhes bibliográficos
Publicado no:Cell Metab
Main Authors: Tharp, Kevin M., Kang, Michael S., Timblin, Greg A., Dempersmier, Jon, Dempsey, Garret E., Zushin, Peter-James H., Benavides, Jaime, Choi, Catherine, Li, Catherine X., Jha, Amit K., Kajimura, Shingo, Healy, Kevin E., Sul, Hei Sook, Saijo, Kaoru, Kumar, Sanjay, Stahl, Andreas
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5897043/
https://ncbi.nlm.nih.gov/pubmed/29514068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2018.02.005
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