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LSD1 interacts with Zfp516 to promote UCP1 Transcription and Brown Fat Program

Zfp516, a brown fat (BAT) enriched and cold-inducible transcription factor, promotes transcription of UCP1 and other BAT-enriched genes for non-shivering thermogenesis. Here, we identify lysine specific demethylase 1 (LSD1) as a direct binding partner of Zfp516. We show that, through interaction wit...

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Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Sambeat, Audrey, Gulyaeva, Olga, Dempersmier, Jon, Tharp, Kevin, Stahl, Andreas, Paul, Sarah M., Sul, Hei Sook
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4916264/
https://ncbi.nlm.nih.gov/pubmed/27264172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.05.019
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