Unraveling endothelin-1 induced hypercontractility of human pulmonary artery smooth muscle cells from patients with pulmonary arterial hypertension

Contraction of human pulmonary artery smooth muscle cells (HPASMC) isolated from pulmonary arterial hypertensive (PAH) and normal (non-PAH) subject lungs was determined and measured with real-time electrical impedance. Treatment of HPASMC with vasoactive peptides, endothelin-1 (ET-1) and bradykinin...

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Publicado en:PLoS One
Main Authors: Wilson, Jamie L., Warburton, Rod, Taylor, Linda, Toksoz, Deniz, Hill, Nicholas, Polgar, Peter
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2018
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5897024/
https://ncbi.nlm.nih.gov/pubmed/29649319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0195780
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