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Participation of PLK1 and FOXM1 in the hyperplastic proliferation of pulmonary artery smooth muscle cells in pulmonary arterial hypertension

Vascular smooth muscle cells from the pulmonary arteries (HPASMC) of subjects with pulmonary arterial hypertension (PAH) exhibit hyperplastic growth. The PAH HPASMC display an increased sensitivity to fetal bovine serum (FBS) and undergo growth at a very low, 0.2%, FBS concentration. On the other ha...

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Bibliografiske detaljer
Udgivet i:PLoS One
Main Authors: Wilson, Jamie L., Wang, Lizhen, Zhang, Zeyu, Hill, Nicholas S., Polgar, Peter
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6705859/
https://ncbi.nlm.nih.gov/pubmed/31437238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0221728
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