Perturbations of Native Membrane Protein Structure in Alkyl Phosphocholine Detergents: A Critical Assessment of NMR and Biophysical Studies

[Image: see text] Membrane proteins perform a host of vital cellular functions. Deciphering the molecular mechanisms whereby they fulfill these functions requires detailed biophysical and structural investigations. Detergents have proven pivotal to extract the protein from its native surroundings. Y...

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Publicat a:Chem Rev
Autors principals: Chipot, Christophe, Dehez, François, Schnell, Jason R., Zitzmann, Nicole, Pebay-Peyroula, Eva, Catoire, Laurent J., Miroux, Bruno, Kunji, Edmund R. S., Veglia, Gianluigi, Cross, Timothy A., Schanda, Paul
Format: Artigo
Idioma:Inglês
Publicat: American Chemical Society 2018
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5896743/
https://ncbi.nlm.nih.gov/pubmed/29488756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.chemrev.7b00570
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