Chemoprevention in Patients with Peutz‐Jeghers Syndrome: Lessons Learned

LESSONS LEARNED. Motivating patients to enroll in chemopreventive studies is challenging. Chemoprevention with toxic drugs is not feasible. BACKGROUND. LKB1 mutations are the underlying genetic abnormality causing Peutz‐Jeghers syndrome (PJS) and are a potential target for everolimus. In this phase...

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Detalhes bibliográficos
Publicado no:Oncologist
Main Authors: de Brabander, Justin, Eskens, Ferry A.L.M., Korsse, Susanne E., Dekker, Evelien, Dewint, Pieter, van Leerdam, Monique E., van Eeden, Susanne, Klümpen, Heinz‐Josef
Formato: Artigo
Idioma:Inglês
Publicado em: AlphaMed Press 2018
Assuntos:
Clinical Trial Results
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5896716/
https://ncbi.nlm.nih.gov/pubmed/29371475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1634/theoncologist.2017-0682
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