Large-Scale Clonal Analysis Resolves Aging of the Mouse Hematopoietic Stem Cell Compartment

Aging is linked to functional deterioration and hematological diseases. The hematopoietic system is maintained by hematopoietic stem cells (HSCs), and dysfunction within the HSC compartment is thought to be a key mechanism underlying age-related hematopoietic perturbations. Using single-cell transpl...

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Bibliographic Details
Published in:Cell Stem Cell
Main Authors: Yamamoto, Ryo, Wilkinson, Adam C., Ooehara, Jun, Lan, Xun, Lai, Chen-Yi, Nakauchi, Yusuke, Pritchard, Jonathan K., Nakauchi, Hiromitsu
Format: Artigo
Language:Inglês
Published: Cell Press 2018
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5896201/
https://ncbi.nlm.nih.gov/pubmed/29625072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2018.03.013
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