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Wnt3a ligand facilitates autophagy in hippocampal neurons by modulating a novel GSK-3β-AMPK axis

BACKGROUND: In the adult central nervous system (CNS), Wnt signaling regulates dendritic structure and synaptic plasticity. The Wnt signaling pathway can be divided into the canonical (β-catenin-dependent) and non-canonical pathways. In the canonical pathway, the binding of canonical ligands such as...

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Bibliografiska uppgifter
I publikationen:Cell Commun Signal
Huvudupphovsmän: Ríos, Juvenal A., Godoy, Juan A., Inestrosa, Nibaldo C.
Materialtyp: Artigo
Språk:Inglês
Publicerad: BioMed Central 2018
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5896060/
https://ncbi.nlm.nih.gov/pubmed/29642895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12964-018-0227-0
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