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Quantitative characterization of all single amino acid variants of a viral capsid-based drug delivery vehicle
Self-assembling proteins are critical to biological systems and industrial technologies, but predicting how mutations affect self-assembly remains a significant challenge. Here, we report a technique, termed SyMAPS (Systematic Mutation and Assembled Particle Selection), that can be used to character...
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| Publicado no: | Nat Commun |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5895741/ https://ncbi.nlm.nih.gov/pubmed/29643335 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-03783-y |
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