Network analysis of SRC-1 reveals a novel transcription factor hub which regulates endocrine resistant breast cancer

Steroid receptor coactivator 1 (SRC-1) interacts with nuclear receptors and other transcription factors (TFs) to initiate transcriptional networks and regulate downstream genes which enable the cancer cell to evade therapy and metastasise. Here we took a top–down discovery approach to map out the SR...

詳細記述

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書誌詳細
出版年:Oncogene
主要な著者: Browne, Alacoque L., Charmsaz, Sara, Varešlija, Damir, Fagan, Ailis, Cosgrove, Nicola, Cocchiglia, Sinéad, Purcell, Siobhan, Ward, Elspeth, Bane, Fiona, Hudson, Lance, Hill, Arnold D., Carroll, Jason S., Redmond, Aisling M., Young, Leonie S.
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group UK 2018
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5895607/
https://ncbi.nlm.nih.gov/pubmed/29367763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-017-0042-x
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