Network analysis of SRC-1 reveals a novel transcription factor hub which regulates endocrine resistant breast cancer

Steroid receptor coactivator 1 (SRC-1) interacts with nuclear receptors and other transcription factors (TFs) to initiate transcriptional networks and regulate downstream genes which enable the cancer cell to evade therapy and metastasise. Here we took a top–down discovery approach to map out the SR...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Oncogene
Egile Nagusiak: Browne, Alacoque L., Charmsaz, Sara, Varešlija, Damir, Fagan, Ailis, Cosgrove, Nicola, Cocchiglia, Sinéad, Purcell, Siobhan, Ward, Elspeth, Bane, Fiona, Hudson, Lance, Hill, Arnold D., Carroll, Jason S., Redmond, Aisling M., Young, Leonie S.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group UK 2018
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5895607/
https://ncbi.nlm.nih.gov/pubmed/29367763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-017-0042-x
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

Antzeko izenburuak