Differential expression of voltage-gated sodium channels in afferent neurons renders selective neural block by ionic direct current

The assertion that large-diameter nerve fibers have low thresholds and small-diameter fibers have high thresholds in response to electrical stimulation has been held in a nearly axiomatic regard in the field of neuromodulation and neuroprosthetics. In contrast to the short pulses used to evoke actio...

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Bibliographic Details
Published in:Sci Adv
Main Authors: Yang, Fei, Anderson, Michael, He, Shaoqiu, Stephens, Kimberly, Zheng, Yu, Chen, Zhiyong, Raja, Srinivasa N., Aplin, Felix, Guan, Yun, Fridman, Gene
Format: Artigo
Language:Inglês
Published: American Association for the Advancement of Science 2018
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Research Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5895440/
https://ncbi.nlm.nih.gov/pubmed/29651458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aaq1438
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