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Swedish Nerve Growth Factor Mutation (NGF(R100W)) Defines a Role for TrkA and p75(NTR) in Nociception

Nerve growth factor (NGF) exerts multiple functions on target neurons throughout development. The recent discovery of a point mutation leading to a change from arginine to tryptophan at residue 100 in the mature NGFβ sequence (NGF(R100W)) in patients with hereditary sensory and autonomic neuropathy...

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Bibliografski detalji
Izdano u:J Neurosci
Glavni autori: Sung, Kijung, Ferrari, Luiz F., Yang, Wanlin, Chung, ChiHye, Zhao, Xiaobei, Gu, Yingli, Lin, Suzhen, Zhang, Kai, Cui, Bianxiao, Pearn, Matthew L., Maloney, Michael T., Mobley, William C., Levine, Jon D., Wu, Chengbiao
Format: Artigo
Jezik:Inglês
Izdano: Society for Neuroscience 2018
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5895035/
https://ncbi.nlm.nih.gov/pubmed/29483280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1686-17.2018
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