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Swedish Nerve Growth Factor Mutation (NGF(R100W)) Defines a Role for TrkA and p75(NTR) in Nociception

Nerve growth factor (NGF) exerts multiple functions on target neurons throughout development. The recent discovery of a point mutation leading to a change from arginine to tryptophan at residue 100 in the mature NGFβ sequence (NGF(R100W)) in patients with hereditary sensory and autonomic neuropathy...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Sung, Kijung, Ferrari, Luiz F., Yang, Wanlin, Chung, ChiHye, Zhao, Xiaobei, Gu, Yingli, Lin, Suzhen, Zhang, Kai, Cui, Bianxiao, Pearn, Matthew L., Maloney, Michael T., Mobley, William C., Levine, Jon D., Wu, Chengbiao
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5895035/
https://ncbi.nlm.nih.gov/pubmed/29483280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1686-17.2018
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