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Purification of Hepatocytes and Sinusoidal Endothelial Cells from Mouse Liver Perfusion

This protocol demonstrates a method for obtaining high yield and viability for mouse hepatocytes and sinusoidal endothelial cells (SECs) suitable for culturing or for obtaining cell lysates. In this protocol, the portal vein is used as the site for catheterization, rather than the vena cava, as this...

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Detalles Bibliográficos
Publicado en:J Vis Exp
Main Authors: Cabral, Fatima, Miller, Colton M., Kudrna, Katrina M., Hass, Blake E., Daubendiek, Jocelyn G., Kellar, Brianna M., Harris, Edward N.
Formato: Artigo
Idioma:Inglês
Publicado: MyJove Corporation 2018
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5894826/
https://ncbi.nlm.nih.gov/pubmed/29553556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/56993
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