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T cell expression of C5a receptor 2 augments murine regulatory T cell generation and regulatory-T-cell-dependent cardiac allograft survival

C5aR2 (C5L2/gp77) is a 7-transmembrane spanning receptor that binds to C5a but lacks motifs essential for G-protein coupling and associated signal transduction. C5aR2 is expressed on immune cells, modulates various inflammatory diseases in mice, and has been shown to facilitate murine and human regu...

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Vydáno v:J Immunol
Hlavní autoři: Verghese, Divya, Demir, Markus, Chun, Nicholas, Fribourg, Miguel, Cravedi, Paolo, Llaudo, Ines, Woodruff, Trent M., Yadav, Pragya, Lira, Sergio A., Medof, M. Edward, Heeger, Peter S.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5894525/
https://ncbi.nlm.nih.gov/pubmed/29436411
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1701638
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