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T cell expression of C5a receptor 2 augments murine regulatory T cell generation and regulatory-T-cell-dependent cardiac allograft survival
C5aR2 (C5L2/gp77) is a 7-transmembrane spanning receptor that binds to C5a but lacks motifs essential for G-protein coupling and associated signal transduction. C5aR2 is expressed on immune cells, modulates various inflammatory diseases in mice, and has been shown to facilitate murine and human regu...
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| Publicado no: | J Immunol |
|---|---|
| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5894525/ https://ncbi.nlm.nih.gov/pubmed/29436411 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1701638 |
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