Recombinant Netrin-1 Binding UNC5B Receptor Attenuates Neuroinflammation and Brain Injury via PPARγ/NFκB Signaling Pathway after Subarachnoid Hemorrhage in Rats

Neuroinflammation is an essential mechanism involved in the pathogenesis of subarachnoid hemorrhage (SAH)-induced brain injury. Recently, Netrin-1 (NTN-1) is well established to exert anti-inflammatory property in non-nervous system diseases through inhibiting infiltration of neutrophil. The present...

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Udgivet i:Brain Behav Immun
Main Authors: Xie, Zongyi, Huang, Lei, Enkhjargal, Budbazar, Reis, Cesar, Wan, Weifeng, Tang, Jiping, Cheng, Yuan, Zhang, John H.
Format: Artigo
Sprog:Inglês
Udgivet: 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5894358/
https://ncbi.nlm.nih.gov/pubmed/29162556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbi.2017.11.012
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