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Iron-dependent cell death as executioner of cancer stem cells

This commentary highlights the findings by Mai, et al. that ironomycin, derivatives of salinomycin, exhibited more potent and selective therapeutic activity against breast cancer stem cells by accumulating and sequestering iron in lysosome, followed by an iron-mediated lysosomal production of reacti...

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Sonraí Bibleagrafaíochta
Foilsithe in:J Exp Clin Cancer Res
Main Authors: Zhao, Bin, Li, Xin, Wang, Ye, Shang, Peng
Formáid: Artigo
Teanga:Inglês
Foilsithe: BioMed Central 2018
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5894200/
https://ncbi.nlm.nih.gov/pubmed/29636068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-018-0733-3
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