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Iron-dependent cell death as executioner of cancer stem cells
This commentary highlights the findings by Mai, et al. that ironomycin, derivatives of salinomycin, exhibited more potent and selective therapeutic activity against breast cancer stem cells by accumulating and sequestering iron in lysosome, followed by an iron-mediated lysosomal production of reacti...
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| Publicado no: | J Exp Clin Cancer Res |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5894200/ https://ncbi.nlm.nih.gov/pubmed/29636068 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-018-0733-3 |
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