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Iron-dependent cell death as executioner of cancer stem cells
This commentary highlights the findings by Mai, et al. that ironomycin, derivatives of salinomycin, exhibited more potent and selective therapeutic activity against breast cancer stem cells by accumulating and sequestering iron in lysosome, followed by an iron-mediated lysosomal production of reacti...
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| Pubblicato in: | J Exp Clin Cancer Res |
|---|---|
| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
BioMed Central
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5894200/ https://ncbi.nlm.nih.gov/pubmed/29636068 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-018-0733-3 |
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