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Iron-dependent cell death as executioner of cancer stem cells

This commentary highlights the findings by Mai, et al. that ironomycin, derivatives of salinomycin, exhibited more potent and selective therapeutic activity against breast cancer stem cells by accumulating and sequestering iron in lysosome, followed by an iron-mediated lysosomal production of reacti...

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Dettagli Bibliografici
Pubblicato in:J Exp Clin Cancer Res
Autori principali: Zhao, Bin, Li, Xin, Wang, Ye, Shang, Peng
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5894200/
https://ncbi.nlm.nih.gov/pubmed/29636068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-018-0733-3
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