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DNA-release by Streptococcus pneumoniae autolysin LytA induced Krueppel-like factor 4 expression in macrophages

The recruitment of myeloid cells to the lung is of utmost importance for the elimination of invading pathogens. We investigated the Streptococcus pneumoniae-dependent induction mechanism of KLF4 in macrophages as a potential regulator of the macrophage immune response. We demonstrated that only viab...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Herta, Toni, Bhattacharyya, Aritra, Bollensdorf, Christian, Kabus, Christin, García, Pedro, Suttorp, Norbert, Hippenstiel, Stefan, Zahlten, Janine
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5893607/
https://ncbi.nlm.nih.gov/pubmed/29636524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-24152-1
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