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Matriptase-2 deficiency protects from obesity by modulating iron homeostasis

Alterations in iron status have frequently been associated with obesity and other metabolic disorders. The hormone hepcidin stands out as a key regulator in the maintenance of iron homeostasis by controlling the main iron exporter, ferroportin. Here we demonstrate that the deficiency in the hepcidin...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Folgueras, Alicia R., Freitas-Rodríguez, Sandra, Ramsay, Andrew J., Garabaya, Cecilia, Rodríguez, Francisco, Velasco, Gloria, López-Otín, Carlos
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5893555/
https://ncbi.nlm.nih.gov/pubmed/29636509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-03853-1
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