Epitope Binding Characteristics for Risk versus Protective DRB1 Alleles for Visceral Leishmaniasis

HLA-DRB1 is the major genetic risk factor for visceral leishmaniasis (VL). We used SNP2HLA to impute HLA DRB1 alleles and SNPTEST to carry out association analyses in 889 human cases and 977 controls from India. NetMHCIIpan2.1 was used to map epitopes and binding affinities across 49 Leishmania vacc...

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Detaylı Bibliyografya
Yayımlandı:J Immunol
Asıl Yazarlar: Singh, Toolika, Fakiola, Michaela, Oommen, Joyce, Singh, Akhil Pratap, Singh, Abhishek Kr., Smith, Noel, Chakravarty, Jaya, Sundar, Shyam, Blackwell, Jenefer M.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2018
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Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5893436/
https://ncbi.nlm.nih.gov/pubmed/29507109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1701764
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