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CONSTITUTIVELY BOUND EGFR-MEDIATED TYROSINE PHOSPHORYLATION OF TLR9 IS REQUIRED FOR ITS ABILITY TO SIGNAL

Mammalian Toll-like receptors (TLR) recognize microbial infection or cell death associated danger signals and trigger appropriate cellular response. These responses determine the strength and the outcome of the host-microbe interaction. The TLRs are transmembrane proteins located on the plasma or th...

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Dettagli Bibliografici
Pubblicato in:J Immunol
Autori principali: Veleeparambil, Manoj, Poddar, Darshana, Abdulkhalek, Samar, Kessler, Patricia M., Yamashita, Michifumi, Chattopadhyay, Saurabh, Sen, Ganes C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5893352/
https://ncbi.nlm.nih.gov/pubmed/29531172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1700691
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