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IDH1 mutation is associated with lower expression of VEGF but not microvessel formation in glioblastoma multiforme
INTRODUCTION: Glioblastoma multiforme (GBM) represents the most malignant primary brain tumor characterized by pathological vascularization. Mutations in isocitrate dehydrogenases 1 and 2 (IDH1 and IDH2) were observed in GBM. We aimed to assess the intra-tumor hypoxia, angiogenesis and microvessel f...
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| Publicado no: | Oncotarget |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Impact Journals LLC
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5893254/ https://ncbi.nlm.nih.gov/pubmed/29662659 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.24536 |
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