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Distinct moieties underlie biphasic H(+) gating of connexin43 channels, producing a pH optimum for intercellular communication
Most mammalian cells can intercommunicate via connexin-assembled, gap-junctional channels. To regulate signal transmission, connexin (Cx) channel permeability must respond dynamically to physiological and pathophysiological stimuli. One key stimulus is intracellular pH (pH(i)), which is modulated by...
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| Publicado no: | FASEB J |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Federation of American Societies for Experimental Biology
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5893178/ https://ncbi.nlm.nih.gov/pubmed/29183963 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201700876R |
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