pH-dependent modulation of voltage gating in connexin45 homotypic and connexin45/connexin43 heterotypic gap junctions

Intracellular pH (pH(i)) can change during physiological and pathological conditions causing significant changes of electrical and metabolic cell–cell communication through gap junction (GJ) channels. In HeLa cells expressing wild-type connexin45 (Cx45) as well as Cx45 and Cx43 tagged with EGFP, we...

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Hlavní autoři: Palacios-Prado, Nicolas, Briggs, Stephen W., Skeberdis, Vytenis A., Pranevicius, Mindaugas, Bennett, Michael V. L., Bukauskas, Feliksas F.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2010
Témata:
Biological Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2906847/
https://ncbi.nlm.nih.gov/pubmed/20445098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1004552107
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