The (95)RGD(97) sequence on the Aα chain of fibrinogen is essential for binding to its erythrocyte receptor

BACKGROUND: Erythrocyte aggregation, a cardiovascular risk factor, is increased by high plasma fibrinogen levels. Here, the effect of different fibrinogen mutations on binding to its human erythrocyte receptor was assessed in order to identify the interaction sites. METHODS: Three fibrinogen variant...

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Dades bibliogràfiques
Publicat a:Int J Nanomedicine
Autors principals: Carvalho, Filomena A, Guedes, Ana Filipa, Duval, Cedric, Macrae, Fraser L, Swithenbank, Luke, Farrell, David H, Ariëns, Robert AS, Santos, Nuno C
Format: Artigo
Idioma:Inglês
Publicat: Dove Medical Press 2018
Matèries:
Original Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5892956/
https://ncbi.nlm.nih.gov/pubmed/29662311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S154523
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