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Predicting essential proteins by integrating orthology, gene expressions, and PPI networks

Identifying essential proteins is very important for understanding the minimal requirements of cellular life and finding human disease genes as well as potential drug targets. Experimental methods for identifying essential proteins are often costly, time-consuming, and laborious. Many computational...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Zhang, Xue, Xiao, Wangxin, Hu, Xihao
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5892885/
https://ncbi.nlm.nih.gov/pubmed/29634727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0195410
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