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Predicting essential proteins by integrating orthology, gene expressions, and PPI networks

Identifying essential proteins is very important for understanding the minimal requirements of cellular life and finding human disease genes as well as potential drug targets. Experimental methods for identifying essential proteins are often costly, time-consuming, and laborious. Many computational...

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Bibliografiske detaljer
Udgivet i:PLoS One
Main Authors: Zhang, Xue, Xiao, Wangxin, Hu, Xihao
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5892885/
https://ncbi.nlm.nih.gov/pubmed/29634727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0195410
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