Nuclear Receptor Subfamily 1 Group D Member 1 Regulates Circadian Activity Of NLRP3 Inflammasome to Reduce the Severity of Fulminant Hepatitis in Mice

BACKGROUND & AIMS: The innate immune system responds not only to bacterial signals, but also to non-infectious danger-associated molecular patterns that activate the NLRP3 inflammasome complex after tissue injury. Immune functions vary over the course of the day, but it is not clear whether thes...

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Veröffentlicht in:Gastroenterology
Hauptverfasser: Pourcet, B, Zecchin, M, Ferri, L, Beauchamp, J, Sitaula, S, Billon, C, Delhaye, S, Vanhoutte, J, Mayeuf-Louchart, A, Thorel, Q, Haas, J, Eeckhoute, J, Dombrowicz, D, Duhem, C, Boulinguiez, A, Lancel, S, Sebti, Y, Burris, T, Staels, B, Duez, H
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2017
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5892845/
https://ncbi.nlm.nih.gov/pubmed/29277561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2017.12.019
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