Conversion to seronegative status after abatacept treatment in patients with early and poor prognostic rheumatoid arthritis is associated with better radiographic outcomes and sustained remission: post hoc analysis of the AGREE study

OBJECTIVE: To evaluate the effects of the T-cell costimulation blocker abatacept on anti-citrullinated protein antibodies (ACPA) and rheumatoid factor (RF) in early rheumatoid arthritis (RA), and associations between changes in serological status and clinical response. METHODS: Post hoc analysis of...

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Опубликовано в: :RMD Open
Главные авторы: Jansen, Diahann T S L, Emery, Paul, Smolen, Josef S, Westhovens, Rene, Le Bars, Manuela, Connolly, Sean E, Ye, June, Toes, René E M, Huizinga, Tom W J
Формат: Artigo
Язык:Inglês
Опубликовано: BMJ Publishing Group 2018
Предметы:
Rheumatoid Arthritis
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5892779/
https://ncbi.nlm.nih.gov/pubmed/29657830
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/rmdopen-2017-000564
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